Serenade of the Seas will sail from Cartagena, Colombia and Colón, Panama in 2025 and 2026.
The Radiance Class vessel is set to conclude Royal Caribbean's first-ever world cruise on September 10, 2024. Afterward, the 90,090 gross registered ton ship will remain in Tampa through March 2025, offering 5- to 9-night cruises to the Caribbean, before relocating to the West Coast for a summer season in Alaska.
Then, Serenade of the Seas will embark on a 13-night Panama Canal cruise from San Diego to Miami on September 19, marking the last time the ship will visit Florida through at least April 2026.
Effective October 5, Serenade will offer cruises to the Southern Caribbean from Cartagena, Colombia and Colón, Panama.
Sailings departing from Cartagena, Colombia will spend a day in Colon, Panama, and vice versa
Similar to many European cruises, all voyages on Serenade of the Seas from Colombia and Panama are "interport" sailings, meaning that guests may choose their embarkation city.
Unlike Caribbean sailings that depart solely from Miami, Fort Lauderdale, or Port Canaveral, interport cruises offer flexibility and a broader choice for travelers, allowing guests to determine which city is most convenient or appealing for their departure.
Currently, Royal Caribbean's Oasis of the Seas is sailing interport cruises, where passengers may embark in Barcelona, Spain or Civitavecchia (Rome), Italy.
Read more: I sailed on a Radiance Class ship
Most itineraries are 7 nights
On October 5, 2025, Serenade will depart from Cartagena, Colombia on a 7-night cruise to Willemstad, Curaçao; Oranjestad, Aruba; and Colón, Panama before returning to Colombia on October 12.
Though all itineraries visit at least two of the ABC (Aruba, Bonaire, and Curaçao) islands, each voyage offers a blend of destinations and experiences. Some, for example, may only visit Bonaire and Curaçao, while others call at Curaçao and Aruba or Aruba and Bonaire.
Select sailings visit all three:
- December 12, 2025 from Colón, Panama
- December 14, 2025 from Cartagena, Colombia
On sailings with three ports of call, including Panama or Colombia, the ship will spend three days at sea.
If you want to sail through the Panama Canal, you will have to book a dedicated Panama Canal cruise
Colón, Panama sits at the entrance to the Panama Canal and is a significant port city for maritime trade. However, it's not located inside the canal. Instead, it serves as a gateway to the canal's operations.
Sailing through the Panama Canal is a bucket list cruise for many, as it offers a unique opportunity to traverse one of the world's most famous engineering marvels.
Do not book a sailing to the Southern Caribbean on Serenade of the Seas in hopes of seeing the canal in person—you'll end up disappointed.
Royal Caribbean offers repositioning cruises through the canal throughout the year, typically in the fall and spring. In 2025, guests may choose from four sailings on two Radiance Class ships: Serenade of the Seas and Radiance of the Seas.
- 16-night Panama Canal cruise on Serenade of the Seas from Fort Lauderdale, Florida to Los Angeles, California on April 13
- 15-night Panama Canal cruise on Radiance of the Seas from Tampa, Florida to Los Angeles, California on April 19
- 13-night Panama Canal cruise on Serenade of the Seas from San Diego, California to Miami, Florida on September 19
- 16-night Panama Canal cruise on Radiance of the Seas from San Diego, California to Fort Lauderdale, Florida on October 4
Updates to Royal Caribbean's Crown & Anchor single supplement benefit
WAAAYTOOO took to Royal Caribbean Blog's discussion forum to share an update they received in their recent Crown & Anchor newsletter.
"Starting August 1, Pinnacle Club and Diamond Plus members with more than 340 points will enjoy a reduced single supplement cruise fare of 125% on all Transatlantic, Transpacific, and Panama Canal sailings," the post reads.
"We want to make booking these popular voyages even easier. For all other sailings, you will continue to enjoy a reduced single supplement fare of 150%."
Read more: Crown and Anchor Society loyalty program info, tips & secrets
This means, for example, if the cruise fare is $1,000 per person, Pinnacle Club and Diamond Plus cruisers would only pay $1,250. Before this update, the fare would have cost $1,500.
The change only applies to Pinnacle Club and Diamond Plus sailors with 340+ cruise points. There's no single supplement benefit for Gold, Platinum, Emerald, or Diamond Crown & Anchor members.
